Caprisa - Scientific Publication

Africa’s response to this Ebola outbreak shows how to shape global health

Abdool Karim S

Nature

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The Bundibugyo Ebolavirus Outbreak: the need for a solidaristic response under the revised International Health Regulations

Abdool Karim S, Faure M

The Lancet Regional Health – Africa

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High-dose pyridoxine and peripheral neuropathy: Considerations for clinicians, pharmacists and policy-makers

Job B, Govender M, Gengiah TN

https://doi.org/10.7196/SAMJ.2026.v116i5.4610

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Urgent need for a reliable rapid diagnostic test for the Ebola epidemic caused by Bundibugyo virus in Africa

Safura Abdool Karim, Sharana Mahomed, Lara Lewis, Salim S Abdool Karim

The Lancet

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Optimizing personalized screening intervals for clinical biomarkers using extended joint models

Mchunu NN, Mwambi H, Reddy T, Yende-Zuma N, Rizopoulos D

Journal of Applied Statistics

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Acceptability and perspectives on clinic-based urine tenofovir testing for antiretroviral therapy adherence monitoring: qualitative findings from a randomized controlled trial in South Africa

Bardon AR, Zondi M, Simoni JM, Tlhaku K, Munatsi P, Bhengu N, Hill E, Khanyile M, Gandhi M, Dorward J, Garrett N, Drain PK

AIDS care

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Pharmacokinetics of Twice-daily Tenofovir Alafenamide in Adults With HIV-associated Tuberculosis on Bictegravir/Emtricitabine/Tenofovir Alafenamide and Rifampicin

Osuala EC, Nkuhairwe IN, Letsoalo MP, Naidoo K, Perumal R, Rooney JF, Wiesner L, Wasmann RE, Denti P, Dooley KE, Naidoo A; INSIGHT Study Team

Clinical Infectious Diseases

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Pre-Human Immunodeficiency Virus (HIV) infection Th17 CD4+ T cells as predictors of early HIV disease progression

Omole TE, Nguyen HM, Marcinow A et al

PLoS Pathogens

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PANORAMIC Trial and CanTreatCOVID Trial Collaborative Groups. Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients

Butler CC, Pinto AD, Harris V, Holmes J, Rahman NM, Cureton L, Hayward G, Richards DB, Lowe DM, Standing JF, Breuer J, Hood K, Png ME, Petrou S, Dorward J, Patel MG, Thomas NPB, Evans P, Hart ND, Jani BD, Hosseini B, Murthy S, McBrien K, Condon A, McDonald EG, Daley P, Greiver M, da Costa BR, Selby P, Jüni P, Lee TC, Shi H, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Saville BR, Khoo SH, Nguyen-Van-Tam JS, Hobbs FDR, Yu LM, Little P

New England Journal of Medicine

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Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potential

Korber B, Seaman MS, Mkhize NN et al

PLoS Pathogens

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Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients

Butler CC, Pinto AD, Harris V, Holmes J et al

New England Journal of Medicine

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Impact of tenofovir alafenamide sub-dermal implant insertion site scarring on acceptability and HIV prevention preferences: a prospective cohort study in Durban, South Africa

Gengiah TN, Lewis L, Harkoo I, Myeni N, Mansoor LE, Abdool Karim SS, Abdool Karim Q

Journal of the International AIDS Society

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Cell-free RNA reveals host and microbial correlates of broadly neutralizing antibody development against HIV

Kowarsky M, Dalman M, Moufarrej MN et al

PLoS Pathogens

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VIBRANT: A phase 1 randomized trial of multi-strain vaginal L. crispatus live biotherapeutic products in people with bacterial vaginosis

Potloane D, Symul L, Ngcapu S, Lewis L et al

Cell Host Microbe

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Ethical design as a prerequisite for translational microbiome science

Passmore JS, Nieves Delgado A, et al

Microbiome

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Lessons learned from viral hepatitis testing that inform law and policy responses to steatotic liver disease

Lazarus JV, Kopka CJ, Nicolàs A, Karim SA et al

Nature Reviews Gastroenterology & Hepatology

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Lessons learned from viral hepatitis testing that inform law and policy responses to steatotic liver disease

Lazarus JV, Kopka CJ, Nicolàs A, Karim SA et al

Nature Reviews Gastroenterology & Hepatology

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Navigating "Wicked" Disagreement in Public Health

Karim SA, Faden R, Barnhill A et al

American Journal of Public Health

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Inflammatory Biomarkers Predicting Major Adverse Cardiovascular Events in People Living With HIV: A Systematic Review and Meta-Analysis

Murray A, Louwman N, Luk A et al

Journal of the International AIDS Society

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Adherence to Oral HIV Pre-exposure Prophylaxis During Pregnancy and the Post-partum Period: Lessons Learned in an Open-Labelled Clinical Trial

Khoza N, Desmond AC, Moodley D

AIDS and Behavior

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Treatment outcomes and drug-related adverse events across four short-course RR-TB regimens in South Africa: A retrospective analysis

Ndjeka N, Perumal R, Romanowski K et al

International Journal of Infectious Diseases

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HLA Class II Protein Expression Regulation Is Strongly Linked to Cis-Acting SNPs. HLA

Vince N, Ramsuran V, Viard M et al

HLA

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Lenacapavir as pre-exposure prophylaxis for HIV prevention

Ebrahim S, Gloeck N, Adam Z et al

Cochrane Database of Systematic Reviews

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Navigating "Wicked" Disagreement in Public Health

Karim SA, Faden R, Barnhill A et al

American Journal of Public Health

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Catalysing future research on the under-recognised burden of post-tuberculosis pulmonary hypertension

Perumal R

African Journal of Thoracic and Critical Care Medicine

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Body mass index (BMI) at RR-TB diagnosis as an independent predictor of treatment outcomes: a retrospective analysis

Mzinyane N, Perumal R, Amusa LB, Chetty D, Shunmugam L, Boodhram R, Narasimmulu R, O'Donnell M, Wolf A, Padayatchi N, Naidoo K

BMC Infectious Diseases

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Quality assessment of data for decentralised antiretroviral therapy referrals and laboratory results in the South African national electronic HIV management register TIER.Net

Naidu L, van der Molen J, Jugathpal V et al

PLOS Global Public Health

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Preventing tuberculosis in advanced HIV disease

Perumal R, Naidoo K

Lancet HIV

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The vaginal microbiome in pregnancy and preterm birth: mechanisms, disparities, and therapeutic opportunities

Pillay N, Short CS, Mzobe GF, Mtshali A, Ngcapu S

NPJ Biofilms Microbiomes

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Quality of life among people with tuberculosis in the Eastern Cape, South Africa: a qualitative study

Bedingfield N, Fiphaza K, Girma M et al

BMC Global and Public Health

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Method Comparison of Dried Blood Spot and Plasma Apolipoprotein B Measurement on a Semi-Automated Analyser: Toward Accessible Lipid Profiling in Resource-Limited Settings

Pitampersad B, Madurai S, Manivannan B, Pillay K, Mahomed S

Analytical Science Advances

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Novel integrase mutations linked to genotypic DTG resistance in African non-B HIV-1 strains: the DTG RESIST study

Han N, Loosli T, Sauermann M et al

Journal of Antimicrobial Chemotherapy

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Point-of-care HIV viral load testing in a community antiretroviral therapy delivery programme: A randomised controlled trial (PHILA)

Dorward J, Tlhaku K, Sookrajh Y et al

PLOS Global Public Health

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Association of human papillomavirus on risk of HIV acquisition in African women: analyses from MTN-020/ASPIRE

Hathaway CL, Brown ER, Cherne S

Journal of the National Cancer Institute

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HLA typing of HLA-A, -B, -C, -DPB1, -DQB1 and -DRB1 loci of 226 individuals from three metropolitan areas in South Africa

Suzuki A, Baguma R, Sawry S et al

Human Immunology

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Enumeration, Phenotyping, and Clinical Associations of Tissue-Resident T Cells in the Ecto- and Endocervix of Women Attending a Colposcopy Clinic

Ssemaganda A, Kahia N, Oo MM

American Journal of Reproductive Immunology

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Approaches to the Management of Virologic Failure on Dolutegravir-Based Antiretroviral Therapy in the 50 Countries With the Highest Adult HIV Prevalence

Nutt CT, Lessells RJ, Muyindike WR et al

Clinical Infectious Diseases

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The cost-effectiveness of male-partner treatment to prevent recurrence of bacterial vaginosis

Zhang Y, Bradshaw CS, Masson L et al

Scientific Reports (Nature)

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Recruiting people who inject drugs (PWID) into research: benefits and challenges of respondent driven sampling (RDS) in a sample in KwaZulu-Natal, South Africa

Milford C, Hardwick TS, Bosman S et al

Substance Abuse Treatment, Prevention, and Policy

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Chlamydia trachomatis-specific T Cell Immunity Reflects Widespread Exposure in South African Adolescents and Young Women

Bunjun R, Lurie M, Dabee S et al

Journal of Infectious Diseases

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Place susceptibility index mapping at local government scale from population-based survey for Sub-Saharan Africa

Lawal O, Okon M, Blanco N et al

PLoS One

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Developing and testing unconditional cash transfer strategies among young adults with first-episode psychosis in South Africa: a study protocol for a pilot randomised control trial (PRS-FEP trial)

Mlay JP, Jamieson L, Ntlantsana V et al

BMJ Open

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Unmet needs of young adults following first-episode psychosis in KwaZulu-Natal, South Africa: Baseline findings from a pilot randomised controlled trial of basic income support

Mlay JP, Ntlantsana V, Gcabashe N et al

South African Journal of Psychiatry

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Safety and immunogenicity of a single dose of Ad26.COV2.S, BNT162b2, or SARS-CoV-2-rS-protein-nanoparticle in previously vaccinated and unvaccinated adults living with and without HIV in South Africa: a phase 2a randomised, observer-blind trial.

Govender V, Reddy T, Maenetje P, Beattie T, Adonis T, Nielson T, Moodley J, Mdluli J, Bhoola A, Angelo S, Panchia R, Mngadi K, Innes C, Brumskine W, Mlotshwa M, Nhlangulela L, Ncube I, Moyo-Gwete T, Moore PL, Keeton RS, Burgers W, Kumar K, Garg N, Tripathi A, Sayed S, Matsimela K, Mchunu N, Wallis R, Edward VA, Churchyard GJ; COVID-19 Vaccine Strategies study group

The Lancet

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Pharmacokinetic modelling as a tool to assess TB treatment adherence: application to the REMEMBER study

Abdelgawad N, Chirehwa M, McIlleron H et al

The International Journal of Tuberculosis and Lung Disease (IJTLD) Open

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Defining the mechanism of cross-reactivity for a SARS-CoV-2 Beta-elicited antibody toward omicron sub-lineages

Ayres F, Lambson B, Mkhize NN, Makhado Z, Mhlanga D, Serage R, Moore PL, Wibmer CK, Moyo-Gwete T.

Structure- A cell press Journal

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Safety, antiviral activity, and pharmacokinetics of long-acting injectable cabotegravir-rilpivirine in virologically suppressed adolescents living with HIV-1 (IMPAACT 2017/MOCHA): 48-week results of a multinational, phase 1/2, single-arm study

Gaur AH, Baltrusaitis K, Capparelli EV et al