Scientific Publications

Analysis of mpox in Angola conflates distinct timelines
Ndembi N, Mercy K, Folayan MO, Abdool Karim SS
The Lancet

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Anatomical and functional characteristics of symptomatic post-TB lung disease
Perumal R, Pillay S, Bagratee N et al
The International Journal of Tuberculosis and Lung Disease

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The gut and lung microbiome across the TB disease spectrum
Perumal R, Somboro AM, Tulsi J, Ngcapu S, Naidoo K
Frontiers in Microbiology

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Neutralizing antibody responses over time in a demographically and clinically diverse cohort of individuals recovered from SARS-CoV-2 acquisition in Africa: A cohort study
Mkhize NN, Li SS, Hu J, Robinson ST, Hoosain Z, Garrett N, Chirenje ZM, Fleurs L, Kaldine H, Modise T, Moore PL, Randhawa AK, Sholukh AM, Hutter J, Polakowski L, Corey L, Gill K, Montefiori DC, Janes H, Karuna S; HVTN 405/HPTN 1901 Study Team
PLoS Global Health

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Safety and immunogenicity of investigational tuberculosis vaccine M72/AS01E-4 in people living with HIV in South Africa: an observer-blinded, randomised, controlled, phase 2 trial
Dagnew AF, Han LL, Naidoo K, Fairlie L, Innes JC, Middelkoop K, Tameris M, Wilkinson RJ, Ananworanich J, Bower D, Schlehuber L, Frahm N, Cinar A, Dunne M, Schmidt AC
Lancet HIV

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Effect of contraceptive methods on the vaginal microbiome and host immune factors
Serrano MG, Edwards D, Ahmed K, Bailey VC, Beksinska M, Edupuganti L, Harryparsad R, D'Hellencourt FL, Meyer B, Mehou-Loko C, Radzey N, Taku O, Williamson AL, Smit J, Spaine K, Zhu B, Jefferson KK, Nanda K, Strauss Iii JF, Morrison CS, Deese J, Masson L, Buck GA
Contraception

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Safety, tolerability, and pharmacokinetics of an annual tenofovir alafenamide silicone subdermal implant in South African women: a two-part, randomised, placebo-controlled, double-blind, first-in-human, phase 1 trial
Gengiah TN, Lewis L, Harkoo I, Mansoor LE, Khan J, Kharva Z, Hassan-Moosa R, Samsunder N, Hankins C, Pozzetto B, Rooney JF, Gogtay J, Moss JA, Baum MM, Abdool Karim SS, Abdool Karim Q
The Lancet HIV

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The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
Ismail SD, Sebaa S, Abrahams B, Nason MC, Mumby MJ, Dikeakos JD, Joseph SB, Moeser M, Swanstrom R, Garrett N, Williamson C, Quinn TC, Abrahams M-R, Redd AD
Journal of Virology

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Review of open-source software for developing heterogeneous data management systems for bioinformatics applications
Silva D, Moir M, Dunaiski M, Blanco N, Murtala-Ibrahim F, Baxter C, de Oliveira T, Xavier JS; INFORM Africa Research Study Group
Bioinformatics Advances

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Genetic variability in HPV 33 and 35 E6 and E7 genes from South African and Mozambican women with different cervical cytology status
Maueia C, Murahwa AT, Carulei O, Taku O, Mbulawa Z, Manjate A, Valey ZO, Mussá T, Williamson AL
Virology Journal

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SARS-CoV-2 vaccines elicit differential Fc effector functions
Manamela NP, Motsoeneng BM, Spencer H, Hermanus T, Mzindle N, Ayres F, Makhado Z, Serage R, Gray GG, Bekker LG, Madhi SA, Moore PL, Richardson SI
iScience

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Humoral, T cell and immune gene expression responses to SARS-CoV-2 vaccination in a small group of children with previous MIS-C
Spracklen TF, Day J, Van Der Ross H, Butters C, Benede N, Walters A, Bunjun R, Moyo-Gwete T, Madzivhandila M, Mendelsohn SC, Scriba TJ, Shey M, Burgers WA, Moore PL, Zühlke LJ, Keeton RS, Webb K
Vaccine

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Hair salons as a promising space to provide HIV and sexual and reproductive health services for young women in Lesotho: a citizen scientist mixed-methods study
Chiaborelli M, Kopeka M, Sekhesa P, Sehrt M, Mohloanyane T, Ballouz T, Menges D, Brown JA, Belus JM, Gerber F, Raeber F, Williams A, Jackson-Perry D, Hyöky M, Conserve DF, Hampanda K, Amstutz A; and the Hair SALON Citizen Scientist Working Group
BMC Public Health

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Cost and clinical flow of point-of-care urine tenofovir testing for treatment monitoring among people living with HIV initiating ART in South Africa
Wang M, Moodley P, Khanyile M, Bulo E, Zondi M, Naidoo K, Sookrajh Y, Dorward J, Gandhi M, Garrett N, Drain PK, Sharma M
Journal of the International AIDS Society

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Experiences of key populations in multidrug-resistant TB and HIV
Nyilana H, Reis K, Seepamore B, Perumal R, Wolf A, Guzman K, Amico KR, Zulu M, Hlathi S, Lu X, Mabuyi T, Nhlangulela N, Perrier R, Wilson M, Friedland G, Naidoo K, Daftary A, Zelnick J, O'Donnell M
The International Journal of Tuberculosis and Lung Disease

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Feasibility and acceptability of GeneXpert MTB/XDR implementation among healthcare workers in three low-middle income African countries.
Keller S, Naidoo K, Zekarias M, Israel-Isah S, Shaka M, Gule G, Naidoo A, Bathnna M, Dlamini-Miti JN, Yae K, Okpokoro E, Abimiku A, Bedru A, Tiemersma EW; TRiAD Study Consortium
PLoS One

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Distinct neutralization sensitivity between adult and infant transmitted/founder HIV-1 subtype C viruses to broadly neutralizing monoclonal antibodies
Ndlovu B, Gounder K, Zikhali N, Singh L, Ntshangase N, Gumede N, Millar J, van Dorsten RT, Grayson NE, Bonsall D, Chaudron SE, Mabuka J, Dong KL, Walker BD, Moore PL, Goulder PJR, Ndung'u T
PLoS Pathogens

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Distinct region-specific neutralization profiles of contemporary HIV-1 clade C against best-in-class broadly neutralizing antibodies
Sutar J, Jayal P, Mullick R, Chaudhary S, Kamble P, Bhowmick S, Kaginkar S, Padwal V, Devadiga P, Neman N, Kitchin D, Kaldine H, Mkhize NN, Ndlovu B, Gounder K, Mukherjee S, Shrivas S, Sharma N, Prasad C, Tewatia S, Parihar N, Kumar N, Kasarpalkar N, Singh B, Mohapatra S, Aquil M, Kumar CV, Dinesha TR, Srikrishnan AK, Shastri J, Agrawal S, Gaikwad S, Mondal S, Bandyopadhyay B, Guha SK, Kale D, Biswas D, Patil D, Paranjape RS, Mukhopadhyay S, Hema, Das R, Kondapi A, Bhor V, Deshpande S, Sok D, Ndung'u T, Moore PL, Murugavel KG, Patel V, Bhattacharya J
Journal of Virology

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Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study
Huang Y, Zhang L, Gelderblom H, Seaton KE, Yates NL, Paez CA, Karuna ST, Andrew P, Gamble T, Robinson ST, Ledgerwood JE, Hyrien O, Walsh SR, Gay CL, Gwira JA, Spiegel HML, Sobieszczyk ME, Mannheimer SB, Edupuganti S, Hurt CB, Stephenson KE, Yu C, Kelley CF, Mahomed S, Siegel M, Yacovone M, Pensiero MN, Donnell D, Cohen MS, Corey L, Gilbert PB, Koup RA, Tomaras GD; VRC 605, HVTN 127/HPTN 087, HVTN 130/HPTN 089, HVTN 136/HPTN 092, and HVTN 140/HPTN 101 study teams
Ebiomedicine

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Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa
Mda P, Mngadi K, Zhang B, Burnham R, Juraska M, Hyrien O, Garrett N, Dubula T, Toni S, Joseph S, Kotze P
Frontiers in Reproductive Health

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Measuring mobility in HIV research in sub-Saharan Africa: a scoping review
Khalifa A, Wallach S, Grabowski MK, Duncan DT, Nalugoda F, Abdool Karim Q, Mathema B
The Journal of the International AIDS Society 

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Perinatal transmission and cure of extensively drug-resistant tuberculosis in an infant
Singh V, Perumal R, Wessels M, Hai F, Lutchminarain K, Naidoo K, Swe-Han KS
African Journal of Thoracic and Critical Care Medicine

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Safety, pharmacokinetics, and neutralisation activity of PGDM1400LS, a V2 specific HIV-1 broadly neutralising antibody, infused intravenously or subcutaneously in people without HIV-1 in the USA (HVTN 140/HPTN 101 part A): a first-in-human, phase 1 randomised trial
Seaton KE, Paez CA, Yu C, Karuna ST, Gamble T, Miner MD, Heptinstall J, Zhang L, Gao F, Yacovone M, Spiegel H, Dumond JB, Anderson M, Piwowar-Manning E, Dye B, Tindale I, Proulx-Burns L, Trahey M, Takuva S, Takalani A, Bailey VC, Kalams SA, Scott H, Mkhize NN, Weiner JA, Ackerman ME, McElrath MJ, Pensiero M, Barouch DH, Montefiori D, Tomaras GD, Corey L, Cohen MS, Huang Y, Mahomed S, Siegel M, Kelley CF; HVTN 140/HPTN 101 study team.
Lancet HIV

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Global Health "With Justice": The Challenges and Opportunities for Human Rights in Global Health Law.
Forman L, Abdool Karim Sufura, Kolawole O. Global Health "With Justice": The Challenges and Opportunities for Human Rights in Global Health Law
Journal of Law, Medicine and Ethics

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Bone Mineral Content, Growth, and Renal Health of Infants With Perinatal Exposure to Maternal Dolutegravir Versus Efavirenz and Tenofovir Disoproxil Fumarate Versus Tenofovir Alafenamide: The Randomized IMPAACT 2010 (VESTED) Trial
Mbengeranwa TG, Ziemba L, Brummel SS, Johnston B, Cassim H, Theron G, Ngqawana Z, Wabwire D, McCarthy K, Shepherd J, Lockman S, Chinula L, Stranix-Chibanda L; IMPAACT 2010/VESTED study team and investigators
JAIDS

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Bone mineral density changes in breastfeeding women with HIV on antiretroviral therapy in Eastern and Southern Africa.
Matovu Kiweewa F, Stranix-Chibanda L, Yende-Zuma N, Dadabhai S, Owor M, Hanley S, Nyati M, Chinula L, Pettifor JM, Brummel SS, Aizire J, Taha TE, Brown TT, Fowler MG; Maternal Bone Health Study team
AIDS

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Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a phase 2, randomised, placebo-controlled trial
Hemmerling A, Mitchell CM, Demby S, Ghebremichael M, Elsherbini J, Xu J, Xulu N, Shih J, Dong K, Govender V, Pillay V, Ismail N, Casillas G, Moodley J, Bergerat A, Brunner T, Liebenberg L, Ngcapu S, Mbano I, Lagenaur L, Parks TP, Ndung'u T, Kwon DS, Cohen CR
Lancet Microbe

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The impact of Covid-19 on food aid systems in South Africa: a cross-sectional mixed-methods study
Abdool Karim Sufura, Kruger P, Erzse A, Rwafa-Ponela T, Nyatela A, Lalla-Edward S
Health Promotion International

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Pre-Human Immunodeficiency Virus (HIV) α4β7hi CD4+ T Cells and HIV Risk Among Heterosexual Individuals in Africa
Omole TE, Nguyen HM, Marcinow A, Oo MM, Jahan N, Ssemaganda A, Severini G, Thomas KK, Celum C, Mugo N, Mujugira A, Kublin J, Corey L, Sivro A, Lingappa JR, Gray G, McKinnon LR
Journal of Infectious Diseases

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BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection
Schmidt AC, Fairlie L, Hellström E, Luabeya Kany Kany A, Middelkoop K, Naidoo K, Nair G, Gela A, Nemes E, Scriba TJ, Cinar A, Frahm N, Mogg R, Kaufman D, Dunne MW, Hatherill M
NEJM

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Aligning Health Promotion Principles With Health Behavior Practice: Experiences With Qualitative Tuberculosis Research
Bedingfield N, Oga-Omenka C, Mantell JE, Masvawure TB, Furin J, McDowell A, Engel N, Daftary A
The American Journal of Health Promotion

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The consequences of SARS-CoV-2 within-host persistence
Sigal A, Neher RA, Lessells RJ
Nature Reviews Microbiology

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IgG antibody response to Mycobacterium tuberculosis curli pili (MTP) in people from different geographical regions in Sub-Saharan Africa
Pillay K, Coetzer T, Connolly C, Pillay B, Chiliza T, Naidoo K, Sutherland J, Ndung'u T, Mayanja-Kizza H, Pillay M
Tuberculosis (Edinb)

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Pharmacokinetics and safety of dolutegravir in children receiving rifampicin tuberculosis treatment in South Africa (ORCHID): a prospective cohort study
Naidoo A, Waalewijn H, Naidoo K, Letsoalo M, Cromhout G, Sewnarain L, Mosia NR, Osuala EC, Wiesner L, Wasmann RE, Denti P, Dooley KE, Archary M; ORCHID study team.
Lancet HIV

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Predicted dolutegravir resistance in people living with HIV in South Africa during 2020-35: a modelling study
Loosli T, Han N, Hauser A, Josi J, Ingle SM, van Sighem A, Wittkop L, Vehreschild J, Ceccherini-Silberstein F, Maartens G, Gill MJ, Sabin CA, Johnson LF, Lessells R, Günthard HF, Egger M, Kouyos RD.
Lancet Global Health

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Mobilising national and regional assets and non-state actors for pandemic preparedness
Sun L, Selbie D, Khan AS,Abdool Karim SS, Legido-Quigley H, Ogunsola FT, Eamer G, Matsoso MP, Bausch DG, Fisher D.
Lancet

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Alignment-free viral sequence classification at scale
van Zyl DJ, Dunaiski M, Tegally H, Baxter C, de Oliveira T, Xavier JS
BMC Genomics

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High burden of human papillomavirus and premalignant cervical lesions among women starting HIV treatment in KwaZulu-Natal, South Africa
Naicker N, Osman F, Naidoo K, Bodley N, Mbambo N, Madlala S, Mhlongo T, Mbatha N, Maphumulo A, Munatsi P, Radebe P, Liebenberg L, Dorward J, Drain PK, Garrett N.
Sexually Transmitted Infections

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Differences in HIV risk factors between South African adolescents and adult women and their association with sexually transmitted infections
Mkhize P, Mehou-Loko C, Maphumulo N, Radzey N, Abrahams AG, Sibeko S, Harryparsad R, Manhanzva M, Meyer B, Radebe P, Liebenberg LJP, Ngcapu S, Ahmed N, Busakwe F, Mqaba N, Archary D, Sivro A, Samsunder N, Potloane D, Horsnell W, Jordan C, Abdool Karim Q, Bekker LG, Passmore JA, Jaspan H, Humphries H, Masson L.
Sexually Transmitted Infections

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Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates
Rajagopalan S, Rourke AK, Asare E, Kohlerschmidt DJ, Das L, Ngema SL, Mulholland CV, Vilchèze C, Mahalingam V, Moodley S, Truebody B, Mackenzie J, Steyn AJC, Perumal R, Berney M, Larsen MH, O'Donnell MR, Escuyer VE, Jacobs WR Jr.
Journal of Infectious Diseases

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Impact of increasing CD4 count threshold eligibility for antiretroviral therapy initiation on advanced HIV disease and tuberculosis prevalence and incidence in South Africa: an interrupted time series analysis
Asare K, Lewis L, van der Molen J, Sookrajh Y, Khubone T, Ngwenya T, Mkhize NS, Lessells RJ, Naidoo K, Sosibo P, Bottomley C, Garrett N, Dorward J.
BMJ Global Health

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Pharmacokinetics and safety of dolutegravir in children receiving rifampicin tuberculosis treatment in South Africa (ORCHID): a prospective cohort study
Anushka Naidoo, PhDa,∙ Hylke Waalewijn, PhDc ∙ Kogieleum Naidoo, PhDa,b ∙ Marothi Letsoalo, MSca ∙ Gabriela Cromhout, MBBSd ∙ Leora Sewnarain, HDEde ∙ Nozibusiso R Mosia, BNURe ∙ Emmanuella C Osuala, MPharma ∙ Prof Lubbe Wiesner, PhDc ∙ Roeland E Wasmann, PhDc ∙ Prof Paolo Denti, PhDc ∙ Prof Kelly E Dooley, MDf,† ∙ Prof Moherndran Archary, PhDe,† on behalf of the ORCHID study team
The Lancet

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Acceptability of an annual tenofovir alafenamide implant for HIV prevention in South African women: findings from the CAPRISA 018 Phase I clinical trial
Tanuja N. Gengiah, Craig J. Heck, Lara Lewis, Leila E. Mansoor, Ishana Harkoo, Nqobile Myeni, Marc M. Baum, John A. Moss, James F. Rooney, Catherine Hankins, Bruno Pozzetto, Salim S. Abdool Karim, Quarraisha Abdool Karim
JIAS

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Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection
Perugino CA, Liu H, Feldman J, Marbourg J, Guy TV, Hui A, Ingram N, Liebaert J, Chaudhary N, Tao W, Jacob-Dolan C, Hauser BM, Mian Z, Nathan A, Zhao Z, Kaseke C, Tano-Menka R, Getz MA, Senjobe F, Berrios C, Ofoman O, Manickas-Hill Z, Wesemann DR, Lemieux JE, Goldberg MB, Nündel K, Moormann A, Marshak-Rothstein A, Larocque RC, Ryan ET, Iafrate JA, Lingwood D, Gaiha G, Charles R, Balazs AB, Pandit A, Naranbhai V, Schmidt AG, Pillai S.
Cell Reports

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Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection.
Perugino CA, Liu H, Feldman J, Marbourg J, Guy TV, Hui A, Ingram N, Liebaert J, Chaudhary N, Tao W, Jacob-Dolan C, Hauser BM, Mian Z, Nathan A, Zhao Z, Kaseke C, Tano-Menka R, Getz MA, Senjobe F, Berrios C, Ofoman O, Manickas-Hill Z, Wesemann DR, Lemieux JE, Goldberg MB, Nündel K, Moormann A, Marshak-Rothstein A, Larocque RC, Ryan ET, Iafrate JA, Lingwood D, Gaiha G, Charles R, Balazs AB, Pandit A, Naranbhai V, Schmidt AG, Pillai S.
Cell Reports

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Improved antibody breadth with an extended primary dose interval of COVID-19 vaccine is overcome by boosters
Ahmed JI, Krosta SJ, Reimer MN, Cheung W, Mesa C, Lopez C, Chua RJ, Alsattari F, Robinson A, Manguiat K, Jahan N, Abrenica B, Harris A, Cachero K, Fabia R, Walker J, Oo MM, Stein D, Ji H, Su RC, McLaren PJ, McKinnon LR, Ball TB, Wood H, Kim J, Kiazyk SA, Card CM.
Frontiers in Immunology

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Exploring the female genital tract mycobiome in young South African women using metaproteomics
Gangiah TK, Alisoltani A, Potgieter M, Bell L, Ross E, Iranzadeh A, McDonald Z, Allali I, Dabee S, Barnabas S, Blackburn JM, Tabb DL, Bekker LG, Jaspan HB, Passmore JS, Mulder N, Masson L.
Microbiome

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High mortality among patients with tuberculosis accessing primary care facilities: secondary analysis from an open-label cluster-randomised trial
Naidoo K, Yende-Zuma N, Moodley M, Made F, Perumal R, Gengiah S, Ngozo J, Padayatchi N, Nunn A, Abdool Karim SS.
EClinicalMedicine

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Spatial Analysis of HIV Determinants Among Females Aged 15-34 in KwaZulu Natal, South Africa: A Bayesian Spatial Logistic Regression Model
Chireshe E, Chifurira R, Chinhamu K, Batidzirai JM, Kharsany ABM.
International Journal of Environmental Research and Public Health

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Strategies for relapse prevention among people with schizophrenia in KwaZulu-Natal Province, South Africa: Healthcare providers' perspectives
Mlay JP, Naidu T, Ramlall S, Patankar K, Israel K, Esquivel L, Curran L, Mhlungu SS, Zondi M, Lessells R, Tomita A, Manuel JI.
PloS One

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Surveillance for Chlamydia trachomatis variants escaping detection with the Aptima Combo 2 assay in Canada from 2019 to 2021
Roy F, Beirnes J, LeBlanc JJ, Gibbons S, Sivro A, Severini A; Canadian Public Health Laboratory Network (CPHLN) Chlamydia Variant Working Group.
Microbiology Spectrum

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The persistent pool of HIV-1-infected cells is formed episodically during untreated infection
Council OD, Tyers L, Moeser M, Sondgeroth A, Spielvogel E, Richardson BD, Doolabh D, Zhou S, Emery A, Archin NM, Shook-Sa B, Margolis DM, Abdool Karim SS, Kosakovsky Pond S, Garrett N, Abrahams M-R, Joseph SB, Williamson C, Swanstrom R.
Journal of Virology

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Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis
Garcia-Prats AJ, Garcia-Cremades M, Cox V, Kredo T, Dunbar R, Schaaf HS, Seddon JA, Furin J, Achar J, Radke K, Sachs T, Abubakirov A, Ahmed S, Akkerman OW, Al Ani NA, Amanullah F, Ahmad N, Anderson LF, Asfaw M, Bango F, Bauer T, Becerra M, Boeree M, Brinkmann F, Brown R, Brust J, Campbell JR, Carvalho AC, Carvalho I, Cegielski JP, Centis R, Chan ED, Chauhan S, Chiang SS, Chan PC, D'Ambrosio L, Dalcolmo M, Daneilyan N, de Vries G, Draper HR; endTB Study Group; Fairlie L, Francis JR, Franke M, Gegia M, Restrepo CG, Guenther A, Gureva T, Haecker B, Harausz E, Hewison C, Hicks RM, Huerga H, Hughes J, Isaakidis P, Kadri SM, Khan MA, Kotrikadze T, Kuksa L, Lachenal N, Lange C, Lecca L, Lopez-Varela E, Lucena S, Mariandyshev A, Mattoo S, Mendez-Echevarria A, Migliori GB, Mitnick C, Mohr-Holland E, Mulanda W, Murzabakova T, Myrzalieve B, Ndjeka N, Niemann S, Ozere I, Padayatchi N, Parmar M, Parpieva N, Manzur-Ul-Alam M, Rybak N, Sachdeva KS, Salmon K, Santiago-Garcia B, Schaub D, Shah I, Shah S, Shah V, Sharma S, Shim TS, Shin S, Sinha A, Skrahina A, Solanki H, Solans BP, Soriano-Arandes A, Toktogonova A, van der Werf T, Velásquez GE, Williams B, Yim JJ, Savic R, Hesseling A.
Lancet Child Adolescent Health

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Heterologous Immunization with Improved HIV-1 Subtype C Vaccines Elicit Autologous Tier 2 Neutralizing Antibodies with Rapid Viral Replication Control After SHIV Challenge
Chege GK, Chapman RE, Keyser AT, Adams CH, Benn K, van Diepen MT, Douglass N, Lambson B, Hermanus T, Moore PL, Williamson AL.
Viruses

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Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern
Bhiman JN, Madzorera VS, Mkhize Q, Scheepers C, Hermanus T, Ayres F, Makhado Z, Moyo-Gwete T, Crowther C, Singh B, Fortuin M, Marinda E, Jooste S, Zuma K, Zungu N, Morris L, Puren A, Simbayi L, Moyo S, Moore PL.
Scientific Reports

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Evolving Epidemiology of Mpox in Africa in 2024
Ndembi N, Folayan MO, Komakech A, Mercy K, Tessema S, Mbala-Kingebeni P, Ngandu C, Ngongo N, Kaseya J, Abdool Karim SS.
NEJM

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Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development
Hesselman MC, Zeeb M, Rusert P, Pasin C, Mamrosh J, Kariuki S, Pichler I, Sickmann M, Kaufmann MM, Schmidt D, Friedrich N, Metzner KJ, Rindler A, Kuster H, Adams C, Thebus R, Huber M, Yerly S, Leuzinger K, Perreau M, Koller R, Dollenmaier G, Frigerio S, Westfall DH, Deng W, deCamp AC, Juraska M, Edupuganti S, Mgodi N, Murrell H, Garrett N, Wagh K, Mullins JI, Williamson C, Moore PL, Günthard HF, Kouyos RD, Trkola A
Cell Host Microbe

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Virologic Failure and Drug Resistance After Programmatic Switching to Dolutegravir-based First-line Antiretroviral Therapy in Malawi and Zambia
Skrivankova VW, Huwa J, Muula G, Chiwaya GD, Banda E, Buleya S, Chihota B, Chintedza J, Bolton C, Tweya H, Kalua T, Hossmann S, Kouyos R, Wandeler G, Egger M, Lessells RJ.
Clinical Infectious Diseases

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Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study
Hamilton F, Schurz H, Yates TA, Gilchrist JJ, Möller M, Naranbhai V, Ghazal P, Timpson NJ; Genes & Health Research Team; International Tuberculosis Host Genetics Consortium; Parks T, Pollara G.
Lancet Microbe

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Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial
Harris V, Holmes J, Gbinigie-Thompson O, Rahman NM, Richards DB, Hayward G, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Ahmed H, Carson-Stevens A, Nguyen-Van-Tam JS, Patel MG, Saville BR, Francis N, Thomas NPB, Evans P, Dobson M, Png ME, Lown M, van Hecke O, Jani BD, Hart ND, Butler D, Cureton L, Patil M, Andersson M, Coates M, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Yu LM, Hobbs FDR, Little P, Butler CC; PANORAMIC Trial Collaborative Group.
Lancet Infectious Diseases

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Novel polymorphic and copy number diversity in the antibody IGH locus of South African individuals
Marsden AA, Corcoran M, Hedestam GK, Garrett N, Karim SS, Moore PL, Kitchin D, Morris L, Scheepers C.
Immunogenetics

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Resistance mutations that distinguish HIV-1 envelopes with discordant VRC01 phenotypes from multi-lineage infections in the HVTN703/HPTN081 trial: implications for cross-resistance
Cohen P, Lambson BE, Mkhize NN, Moodley C, Yssel AEJ, Moyo-Gwete T, York T, Gwashu-Nyangiwe A, Ndabambi N, Thebus R, Juraska M, deCamp AC, Williamson BD, Magaret CA, Gilbert PB, Westfall D, Deng W, Mullins JI, Morris L, Williamson C, Moore PL.
Journal of Virology

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Resistance mutations that distinguish HIV-1 envelopes with discordant VRC01 phenotypes from multi-lineage infections in the HVTN703/HPTN081 trial: implications for cross-resistance
Cohen P, Lambson BE, Mkhize NN, Moodley C, Yssel AEJ, Moyo-Gwete T, York T, Gwashu-Nyangiwe A, Ndabambi N, Thebus R, Juraska M, deCamp AC, Williamson BD, Magaret CA, Gilbert PB, Westfall D, Deng W, Mullins JI, Morris L, Williamson C, Moore PL.
Journal of Virology

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