Scientific Publications

Evaluation of Time to Detection of Mycobacterium tuberculosis in Broth Culture as a Determinant for End Points in Treatment Trials
Weiner M, Prihoda TJ, Burman W, Johnson JL, Goldberg S, Padayatchi N, Duran P, Engle M, Muzanye G, Mugerwa RD, Sturm AW.
Journal Clinical Microbiology 2010; 48(12): 4370–4376.

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The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis
Abdool Karim Q, Abdool Karim SS, Baxter C, Friedland G, Gengiah T, Gray A, Grobler A, Naidoo K, Padayatchi N, El-Sadr W.
South African Medical Journal 2010; 100(12):808-9.

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Microbicides & their implications in HIV prevention
Abdool Karim SS, Baxter C.
Indian Journal of Medical Research 2010; 132(6): 656-659.

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Screening for 'window-period' acute HIV infection among pregnant women in rural South Africa
Kharsany AB, Hancock N, Frohlich JA, Humphries HR, Abdool Karim SS, Abdool Karim Q.
HIV Medicine 2010; 11(10): 661-665.

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Family planning and the Millennium Development Goals
Cates W Jr, Abdool Karim Q, El-Sadr W, Haffner DW, Kalema-Zikusoka G, Rogo K, Petruney T, Averill EM.
Science 2010; 329(5999):1603.

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Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression
Mlotshwa M, Riou C, Chopera D, De Assis Rosa D, Ntale R, Treunicht F, Woodman Z, Werner L, Van Loggerenberg, Mlisana K, Abdool Karim S, Williamson C, Gray CM.
Journal of Virology 2010, 84(22): 12018-12029.

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Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, Kharsany ABM, Sibeko S, Mlisana KP, Omar Z, Gengiah TN, Maarschalk S, Arulappan N, Mlotshwa M, Morris L, Taylor D, on behalf of the CAPRISA 004 Trial Group.
Science 2010; 329(5996):1168-1174.

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Factors Affecting first-month Adherence to Antiretroviral Therapy Among HIV Positive Adults in South Africa
Maqutu D, Zewotir T, North D, Naidoo K, Grobler A.
African Journal of AIDS Research 2010; 9(2):117-124.

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How ethical is your clinical trial?
Miller L, Folayan M, Allman D, Nkala B, Kasirye LM, Mingote LR, Calazans G, Mburu R, Ntombela F, Ditmore M.
International Journal of Clinical Practice 2010; 64(9):1179-82.

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Case series of the long-term psychosocial impact of drug- resistant tuberculosis in HIV-negative medical doctors
Padayatchi N, Daftary A, Moodley T, Madansein R, Ramjee A.
International Journal of Tuberculosis and Lung Diseases 2010; 14(8):960–966.

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High Treatment Failure and Default Rates for Patients with MDR TB in KwaZulu-Natal, South Africa, 2000-2003
Brust JCM, Gandhi NR, Carrara H, Osburn G, Padayatchi N
Int J Tuberc Lung Dis. 2010; 14(4):413-419.

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Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
Alexandre KB, Gray ES, Lambson BE, Moore PL, Choge IA, Mlisana K, Abdool Karim SS, McMahon J, O’Keefe B, Chikwamba R, Morris L.
Virology 2010; 402(1):187-196

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Immune evaluation of HIV-infected and noninfected pre-eclamptics.
Naidoo K, Pupuma BSX, Moodley J.
South African Family Practice 2010; 52(2):159-160.

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HIV and maternal mortality: turning the tide.
Abdool Karim Q, AbouZahr C, Dehne K, Mangiaterra V, Moodley J, Rollins N, Say L, Schaffer N, Rosen JE, de Zoysa I.
Lancet 2010; 375(9730): 1948-1949.

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Preventing HIV Infection in Women:A Global Health Imperative.
Abdool Karim Q, Sibeko S, Baxter C.
Clinical Infectious Diseases 2010; 50(10):S122–S129.

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Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression.
Roberts L, Passmore J-AS, Williamson C, Little F, Bebell LM, Mlisana K, Burgers WA, van Loggerenberg F, Walzlf G, Djoba Siaway JF, Abdool Karim Q, Abdool Karim SS.
AIDS 2010; 24(6):819-31.

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High Treatment Failure and Default Rates for Patients with MDR TB in KwaZulu-Natal South Africa, 2000-2003
Brust JCM, Padayatchi N, Gandhi NR, Carrara H, Osburn G.South Africa, 2000-2003.
International Journal of Tuberculosis and Lung Disease 2010; 14(4):413-419.

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High Incidence of Hospital Admissions With Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis Among South African Health Care Workers
O’Donnell MR, Jarand J, Loveday M, Padayatchi N, Zelnick J, Werner L, Naidoo K, Master I, Osburn G, Kvasnovsky C, Shean K, Pai M, Van der Walt M,Horsburgh CR, Dheda K.
Annals of Internal Medicine 2010; 153(8):516-522.

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Timing of Initiation of Antiretroviral Drugs during Tuberculosis Therapy
Abdool Karim SS, Naidoo K, Grobler A, Padayatchi N, Baxter C, Gray A, Gengiah T, Nair G, Bamber S, Singh A, Khan M, Pienaar J, El-Sadr W, Friedland G, Abdool Karim Q.
New England Journal of Medicine 2010; 362(8):697-706.

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AIDS research must link to local policy
Abdool Karim SS, Abdool Karim Q.
Nature 2010; 463: 733-734.

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Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure
Treurnicht FK, Seoighe C, Martin DP, Wood N, Abrahams MR, de Assis Rosa D, Bredell H, Woodman Z, Hide W, Mlisana K, Abdool Karim S, Gray CM, Williamson C.
Virology 2010; 396(2): 213-225.

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APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load
Reddy K, Winkler CA, Werner L, Mlisana K, Abdool Karim SS, Ndung'u T; CAPRISA Acute Infection Study Team
AIDS 2010; 24(2):195-204.

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HIV-Selectest Enzyme Immunoassay and Rapid Test: Ability To Detect Seroconversion following HIV-1 Infection
Khurana S, Norris PJ, Haynes BF, Park S, Mlisana K, Abdool Karim S, Hecht FM, Nemo G, Mulenga J, Chomba E, Hunter E, Allen S, Graham B, Women’s Interagency HIV Study, the Multicenter AIDS Cohort Study, Busch MP, Golding HJ.
Journal of Clinical Microbiology 2010; 48(1):281-285.

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