1.    Prevention and Epidemiology: Several descriptive studies have been undertaken in Vulindlela to better understand the epidemiology, risk factors and vulnerability to high rates of HIV infection in young people as a prelude to the current trial of an innovative strategy to prevent HIV in this important group.

2.    Microbicides:  Antiretroviral based microbicide, Tenofovir gel, is being investigated to assess its potential in preventing HIV infection and its impact on natural history of HIV infection

3.    HIV pathogenesis and vaccines: Acute HIV infection is being investigated to generate new knowledge on how viral and host factors impact on the risk of HIV and its natural progression as a key contribution to vaccine development and testing.

4.    HIV and TB treatment: Clinical trials are being conducted to address the key questions and challenges facing co-treatment of HIV and TB. While not primarily a research focus, CAPRISA runs an AIDS care and treatment programme to care for the communities it serves and the study participants who become HIV infected in CAPRISA studies.

Prevention and Epidemiology

Microbicides Research

HIV pathogenesis and Vaccines

HIV and TB treatment Research